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Journal of Exercise Physiology and Health SciencesJournal of Exercise Physiology and Health Sciences

This study aims to explore the response of beta-endorphins to variations in exercise intensity in the context of exercise physiology. Beta-endorphins, endogenous opioid peptides produced in the pituitary gland, play an important role in the regulation of pain and mood. The study involved 30 active participants who underwent an eight-week exercise program with a frequency of three times a week. The research method included measuring beta-endorphin levels before and after the exercise intervention using the ELISA technique. The results showed that at low to moderate intensities (40% and 60% VO2max), beta-endorphin levels did not increase significantly, with values of about 4.8 pmol/l and 6.3 pmol/l, while at high intensities (80% VO2max), levels increased significantly to about 16.1 pmol/l. In addition, a comparison between HIIT (High-Intensity Interval Training) and moderate aerobic exercise showed that HIIT resulted in a greater increase in endorphin release, although participants also reported discomfort during high-intensity sessions. The beta-endorphin response appears to be consistent between the sexes, but the catecholamine response shows significant differences, with higher levels in men. These findings emphasize the importance of considering gender, duration, and gender factors in research on hormonal responses to exercise, as well as its implications for long-term mental and physical health through regular physical activity.

This study provides a better understanding of how various factors affect beta-endorphin levels in the body.Increased levels of beta-endorphins are associated with higher exercise intensity and certain types of exercise such as HIIT, as well as suggesting gender differences in hormonal responses.By taking these factors into account, exercise programs can be designed to maximize mental and physical health benefits through proper physical activity arrangements.

Penelitian lebih lanjut perlu dilakukan untuk menginvestigasi mekanisme spesifik yang mendasari perbedaan respons beta-endorphin antara jenis kelamin, dengan mempertimbangkan faktor hormonal dan metabolisme yang mungkin berperan. Selain itu, studi prospektif jangka panjang diperlukan untuk mengevaluasi dampak latihan intensitas tinggi secara berkelanjutan terhadap kesehatan mental dan fisik, termasuk potensi efek samping dan strategi untuk meminimalkan ketidaknyamanan. Terakhir, penelitian di masa depan dapat mengeksplorasi efektivitas intervensi berbasis olahraga yang dipersonalisasi, yang disesuaikan dengan respons beta-endorphin individu, untuk mengoptimalkan manfaat terapeutik bagi individu dengan kondisi seperti depresi, kecemasan, atau nyeri kronis, dengan mempertimbangkan bahwa respons beta-endorphin dapat bervariasi secara signifikan antar individu.

  1. Effect of Hypnoanesthesia on Endogenous Opioids (Beta Endorphin and Enkephalin) | Pharmacognosy Journal.... phcogj.com/article/1972Effect of Hypnoanesthesia on Endogenous Opioids Beta Endorphin and Enkephalin Pharmacognosy Journal phcogj article 1972
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