JURNALFKIPUNTADJURNALFKIPUNTAD

Jurnal Akademika KimiaJurnal Akademika Kimia

Dental and oral health problems are one of the problems that need attention. The oral cavity is colonized by various microflora and some bacteria, so it is necessary to develop additional oral cleaning methods besides brushing teeth. Mouthwash with natural ingredients, such as a combination of chitosan and Eucalyptus grandis, is the right choice. Chitosan is a type of water-soluble chitosan characterized using FT-IR. Meanwhile, Eucalyptus grandis was isolated using the Stahl method to obtain its essential oil. Mouthwash was evaluated through organoleptic testing, pH, viscosity, and antimicrobial testing. The most optimal formula is formula III, with an inhibition zone diameter of 11.9 ± 1.5 mm for Streptococcus mutans bacteria, 12.8 ± 0.9 mm for Staphylococcus aureus, and 12.2 ± 0.15 mm for Candida albicans.

The study successfully developed a mouthwash formulation using natural ingredients, specifically chitosan and Eucalyptus grandis.Formula III demonstrated the most optimal results in antimicrobial testing against Streptococcus mutans, Staphylococcus aureus, and Candida albicans.These findings suggest that this natural mouthwash formulation has the potential to be an effective alternative to conventional mouthwashes.

Penelitian lebih lanjut perlu dilakukan untuk menguji efektivitas jangka panjang dari mouthwash formula III dalam mencegah pembentukan plak dan gingivitis pada manusia. Studi komparatif antara mouthwash formula III dengan mouthwash komersial yang mengandung chlorhexidine perlu dilakukan untuk mengevaluasi efikasi dan profil keamanan masing-masing. Pengembangan formulasi mouthwash yang lebih inovatif dengan penambahan bahan alami lain yang memiliki sifat antimikroba, seperti ekstrak teh hijau atau minyak atsiri tanaman lain, dapat dieksplorasi untuk meningkatkan efektivitas dan variasi rasa mouthwash.

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