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Majalah Obat TradisionalMajalah Obat TradisionalU Groh is a coconut (Cocos nucifera L.) in which the meat has not been formed yet, and its shell is consumed as a salad by the Acehnese people. This study aims to determine the phytochemicals, GC-MS analysis, and activity of coir and shell U Groh against S. aureus and E. coli bacteria. Chemical compounds were analyzed using reagents and GC-MS. Antibacterial activity was tested using well diffusion with concentrations of 5, 10, 20, and 40%. Coir and shells contain flavonoids, tannins, and saponins. GC-MS analysis shows the coir contains 20 compounds, among others Alpha. - Bisabololoxide B-Acetate, Hexadecanoic acid, Hexadecanoic acid methyl ester, 9 octadecenoic acid methyl ester, Stigmasterol, and gamma. -Sitosterol, whereas 16 compounds for the shell Hexadecanoic acid, Hexadecanoic acid methyl ester, and Stigmast-5-en-3-ol. The highest activity of coir and shell U Groh against E. coli and S. aureus was a concentration of 40%. The antibacterial activity of U Groh coir and shell extract was more effective in inhibiting S. aureus than E. coli. Coir ethanol extract and its shell formed inhibition zones with diameters of 13.7 mm and 13.4 mm, respectively, against S. aureus, and the diameters against E. coli were 11.3 mm and 11.03 mm, respectively. The extract ethanol of coir and shell U Groh has good potential as an antibacterial.
The study concludes that U Groh coir and shell contain flavonoids, tannins, and saponins.GC-MS analysis identified various compounds in both coir and shell extracts.The highest antibacterial activity was observed at a concentration of 40% against both E.These findings suggest the potential of U Groh coir and shell ethanol extracts as antibacterial agents.
Further research should investigate the specific mechanisms of action underlying the antibacterial activity of U Groh coir and shell extracts, potentially focusing on the interaction between identified phytochemicals and bacterial cell structures. Additionally, studies are needed to evaluate the efficacy of these extracts in in-vivo models of infection to assess their potential as therapeutic agents. Finally, research could explore the optimal extraction methods and formulation strategies to enhance the stability and bioavailability of the active compounds, paving the way for the development of novel antibacterial products. These investigations, building upon the current findings, could unlock the full medicinal potential of this traditionally used resource and contribute to addressing the growing challenge of antibiotic resistance.
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