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Jurnal Perikanan Pantura (JPP)Jurnal Perikanan Pantura (JPP)

Vibrio harveyi is a significant bacterial pathogen causing diseases in marine and brackish water fish, leading to reduced product quality, food safety risks, and substantial economic losses globally. Its pathogenicity is linked to biofilm formation, regulated by the quorum sensing (QS) system, enhancing bacterial virulence and antibiotic resistance. Targeting the QS system is a promising approach for managing V. harveyi infections in aquaculture. Octopus ink extract, rich in bioactive compounds like alkaloids, has attracted attention. This study evaluates the effectiveness of octopus ink extract as a quorum quenching (QQ) agent in preventing biofilm formation by V. harveyi in aquaculture. A systematic literature review was conducted, analyzing relevant scientific publications. The findings indicate that active components in octopus ink can interrupt bacterial cell-to-cell communication by blocking QS autoinducers, reducing virulence gene expression and inhibiting biofilm formation without affecting bacterial viability. This strategy may minimize antibiotic resistance. Overall, octopus ink extract shows strong potential as an effective, environmentally friendly quorum quenching agent and may be developed as an immunostimulant to enhance fish health and promote sustainable aquaculture practices.

Octopus ink extract demonstrates potential as a quorum quenching agent for inhibiting Vibrio harveyi biofilm formation in aquaculture.Bioactive compounds, particularly alkaloids, can disrupt bacterial cell-to-cell communication and reduce virulence factor expression.This approach offers an innovative and eco-friendly strategy to lower infection risks in cultured fish while limiting antibiotic resistance.

Penelitian lebih lanjut diperlukan untuk mengidentifikasi senyawa aktif spesifik dalam tinta gurita yang berperan dalam aktivitas quorum quenching. Studi lapangan perlu dilakukan untuk menilai efektivitas dan keamanan ekstrak tinta gurita pada skala budidaya. Selain itu, pengembangan formulasi produk berbasis ekstrak tinta gurita sebagai agen antipatogenik dan imunostimulan dapat menjadi langkah strategis dalam mendukung akuakultur berkelanjutan. Penelitian lanjutan juga dapat mengeksplorasi sinergi antara ekstrak tinta gurita dengan probiotik atau senyawa alami lainnya untuk meningkatkan efektivitasnya dalam mengendalikan infeksi V. harveyi. Investigasi lebih mendalam mengenai mekanisme molekuler bagaimana senyawa aktif dalam tinta gurita berinteraksi dengan sistem quorum sensing bakteri juga penting untuk mengoptimalkan penggunaannya. Terakhir, studi tentang potensi penggunaan tinta gurita dari spesies gurita yang berbeda dan pengaruh kondisi lingkungan terhadap kandungan senyawa aktifnya dapat memberikan wawasan tambahan untuk pengembangan aplikasi akuakultur yang lebih efektif.

  1. Effectiveness of Octopus (Octopus sp.) Ink Exctract on the Growth of Catfish (Clarias sp.) Infected with... journal.unram.ac.id/index.php/jfh/en/article/view/6102Effectiveness of Octopus Octopus sp Ink Exctract on the Growth of Catfish Clarias sp Infected with journal unram ac index php jfh en article view 6102
  2. Potential of Octopus Ink Extract as Anti-Quorum Sensing to Prevent Aeromonas hydrophila Biofilm in Aquaculture... doi.org/10.29303/jbt.v25i1.8438Potential of Octopus Ink Extract as Anti Quorum Sensing to Prevent Aeromonas hydrophila Biofilm in Aquaculture doi 10 29303 jbt v25i1 8438
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