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Bulletin of Chemical Reaction Engineering & CatalysisBulletin of Chemical Reaction Engineering & Catalysis

The catalytic conversion of chitin biomass provides an environment-friendly approach for the synthesis of valuable organonitrogen compounds. Here, we prepared bifunctional Ag/MgO by simple deposition-precipitation method. The catalysts exhibited good catalytic activity for one pot synthesis of N-acetylglycine (AcGly) from N-acetyl glucosamine (NAG), offering a 26.2% yield under optimized conditions. The basic nature of MgO contributed to the retro-aldol of NAG, and Ag species catalyzed the oxidation of intermediate to AcGly. The spent catalyst could be recycled and reused for NAG conversion to AcGly.

The study successfully demonstrated the one-pot conversion of N-acetylglucosamine (NAG) to N-acetylglycine (AcGly) using bifunctional Ag/MgO catalysts.The alkaline supports, particularly MgO, were found to favor the reaction without requiring additional additives.2% under optimized conditions, comparable to previous methods but with a significantly reduced amount of noble metal Ag.

Future research should focus on understanding the deactivation mechanism of the Ag/MgO catalyst during recycling, potentially through detailed structural analysis of the spent catalyst. Investigating alternative, more stable supports for Ag deposition, while maintaining the necessary basicity for retro-aldol reactions, could improve catalyst longevity and reduce performance decline over multiple cycles. Exploring the use of continuous flow reactors for this conversion could enhance process efficiency and scalability, potentially enabling industrial application by providing better control over reaction parameters such as temperature and residence time. Furthermore, examination of the reaction kinetics and the role of different Ag species during the process could lead to a mechanistic understanding for rational catalyst design and optimization.

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